Anticorps Monoclonal anti-PBLD

PBLD Monoclonal Antibody for IF/ICC

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, porc

Applications

IF/ICC

Conjugaison

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

1G11D4

N° de cat : CL488-68317

Synonymes

MAWDBP, MAWD-binding protein, MAWD binding protein, MAWBP, EC:5.1.-.-



Applications testées

Résultats positifs en IF/ICCcellules HEK-293,

Dilution recommandée

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL488-68317 cible PBLD dans les applications de IF/ICC et montre une réactivité avec des échantillons Humain, porc

Réactivité Humain, porc
Hôte / Isotype Mouse / IgG1
Clonalité Monoclonal
Type Anticorps
Immunogène PBLD Protéine recombinante Ag23827
Nom complet phenazine biosynthesis-like protein domain containing
Poids moléculaire observé30 kDa
Numéro d’acquisition GenBankBC009738
Symbole du gène PBLD
Identification du gène (NCBI) 64081
Conjugaison CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Forme Liquide
Méthode de purification Purification par protéine G
Tampon de stockage PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA
Conditions de stockageStocker à -20 °C. Éviter toute exposition à la lumière. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

PBLD, also termed as MAWBP, was first identified from a human liver cDNA library using a yeast two-hybrid technique by Iriyama et al. As the only representative of phenazine biosynthesis-like protein family, PBLD is widely expressed in human tissues, such as brain, heart, lung, liver, pancreas, kidney, and placenta. Its expression is elevated in several diseases processes, including insulin resistance, folate deficiency, and hypotension. PBLD has been proved to be involved in gastric carcinogenesis, PBLD expression was attenuated in gastric cancer (GC) tissues, and negatively regulated the growth and invasion in gastric cancer cell-lines by inhibiting TGF-β1-induced EMT (Epithelial-Mesenchymal Transition).(PMID: 11355021, 17929853, 23687415, 26594798)

Protocole

Product Specific Protocols
IF protocol for CL Plus 488 PBLD antibody CL488-68317Download protocol
Standard Protocols
Click here to view our Standard Protocols
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