Anticorps Monoclonal anti-PBLD
PBLD Monoclonal Antibody for IF/ICC
Hôte / Isotype
Mouse / IgG1
Réactivité testée
Humain, porc
Applications
IF/ICC
Conjugaison
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
1G11D4
N° de cat : CL488-68317
Synonymes
Galerie de données de validation
Applications testées
| Résultats positifs en IF/ICC | cellules HEK-293, |
Dilution recommandée
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Informations sur le produit
CL488-68317 cible PBLD dans les applications de IF/ICC et montre une réactivité avec des échantillons Humain, porc
| Réactivité | Humain, porc |
| Hôte / Isotype | Mouse / IgG1 |
| Clonalité | Monoclonal |
| Type | Anticorps |
| Immunogène | PBLD Protéine recombinante Ag23827 |
| Nom complet | phenazine biosynthesis-like protein domain containing |
| Poids moléculaire observé | 30 kDa |
| Numéro d’acquisition GenBank | BC009738 |
| Symbole du gène | PBLD |
| Identification du gène (NCBI) | 64081 |
| Conjugaison | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
| Forme | Liquide |
| Méthode de purification | Purification par protéine G |
| Tampon de stockage | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA |
| Conditions de stockage | Stocker à -20 °C. Éviter toute exposition à la lumière. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
PBLD, also termed as MAWBP, was first identified from a human liver cDNA library using a yeast two-hybrid technique by Iriyama et al. As the only representative of phenazine biosynthesis-like protein family, PBLD is widely expressed in human tissues, such as brain, heart, lung, liver, pancreas, kidney, and placenta. Its expression is elevated in several diseases processes, including insulin resistance, folate deficiency, and hypotension. PBLD has been proved to be involved in gastric carcinogenesis, PBLD expression was attenuated in gastric cancer (GC) tissues, and negatively regulated the growth and invasion in gastric cancer cell-lines by inhibiting TGF-β1-induced EMT (Epithelial-Mesenchymal Transition).(PMID: 11355021, 17929853, 23687415, 26594798)
Protocole
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 488 PBLD antibody CL488-68317 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
