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Anticorps Polyclonal de lapin anti-PCDH21

PCDH21 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17424-1-PBS

Synonymes

Protocadherin-21, PRCAD, Photoreceptor cadherin, KIAA1775, CDHR1

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using PCDH21 Polyclonal antibody (17424-1-AP)

    WB analysis using 17424-1-AP (same clone as 17424-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17424-1-AP (PCDH21 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17424-1-PBS in a different storage buffer formulation.

Informations sur le produit

17424-1-PBS cible PCDH21 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène PCDH21 Protéine recombinante Ag11451
Nom complet protocadherin 21
Masse moléculaire calculée 745 aa, 82 kDa
Poids moléculaire observé110-120 kDa
Numéro d’acquisition GenBankBC038799
Symbole du gène PCDH21
Identification du gène (NCBI) 92211
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). PCDH21 (protocadherin 21), also known as CDHR1, is a photoreceptor-specific cadherin protein containing six ECs and an intracellular domain. The mutations of PCDH21 cause recessive retinal degeneration and autosomal recessive cone-rod dystrophy in humans (PMID: 16288196; PMID: 20805371). The full length of the PCDH21 protein is 120 kDa, the N-terminal soluble fragment is 95 kDa, and the C-terminal fragment is 25 kDa (PMID: 35066146; PMID: 18654668; PMID: 33964272).

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