Anticorps Recombinant de lapin anti-PCDH21

PCDH21 Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241134E10

N° de cat : 84084-3-PBS

Synonymes

241134E10, Cadherin-related family member 1, CDHR1, KIAA1775, Photoreceptor cadherin

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Galerie de données de validation

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  WB analysis of Y79 using 84084-3-RR (same clone as 84084-3-PBS)

  Y79 cells were subjected to SDS PAGE followed by western blot with 84084-3-RR (PCDH21 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84084-3-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP00999-2

  Cytometric bead array standard curve of MP00999-2, PCDH21 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84084-3-PBS. Detection antibody: 84084-2-PBS. Standard: Ag11451. Range: 0.313-40 ng/mL.

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  Affinity and Kinetic Characterization of 84084-3-RR

  Biolayer interferometry (BLl) kinetic assays of 84084-3-RR against Human PCDH21 were performed. The affinity constant is 0.196 nM.

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Informations sur le produit

84084-3-PBS cible PCDH21 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: PCDH21 Protéine recombinante Ag11451
• Nom complet: protocadherin 21
• Masse moléculaire calculée: 745 aa, 82 kDa
• Poids moléculaire observé: 120 kDa
• Numéro d’acquisition GenBank: BC038799
• Symbole du gène: PCDH21
• Identification du gène (NCBI): 92211
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). PCDH21 (protocadherin 21), also known as CDHR1, is a photoreceptor-specific cadherin protein containing six ECs and an intracellular domain. The mutations of PCDH21 cause recessive retinal degeneration and autosomal recessive cone-rod dystrophy in humans (PMID: 16288196; PMID: 20805371). The full length of the PCDH21 protein is 120 kDa, the N-terminal soluble fragment is 95 kDa, and the C-terminal fragment is 25 kDa (PMID: 35066146; PMID: 18654668; PMID: 33964272).

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