Anticorps Recombinant de lapin anti-PCDH21

PCDH21 Recombinant Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

241134E10

N° de cat : 84084-3-RR

Synonymes

PRCAD, Photoreceptor cadherin, KIAA1775, CDHR1, Cadherin-related family member 1

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Galerie de données de validation

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  WB analysis of Y79 using 84084-3-RR

  Y79 cells were subjected to SDS PAGE followed by western blot with 84084-3-RR (PCDH21 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 84084-3-RR

  Biolayer interferometry (BLl) kinetic assays of 84084-3-RR against Human PCDH21 were performed. The affinity constant is 0.196 nM.

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Applications testées

• Résultats positifs en WB: cellules Y79,

Dilution recommandée

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

84084-3-RR cible PCDH21 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: PCDH21 Protéine recombinante Ag11451
• Nom complet: protocadherin 21
• Masse moléculaire calculée: 745 aa, 82 kDa
• Poids moléculaire observé: 120 kDa
• Numéro d’acquisition GenBank: BC038799
• Symbole du gène: PCDH21
• Identification du gène (NCBI): 92211
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). PCDH21 (protocadherin 21), also known as CDHR1, is a photoreceptor-specific cadherin protein containing six ECs and an intracellular domain. The mutations of PCDH21 cause recessive retinal degeneration and autosomal recessive cone-rod dystrophy in humans (PMID: 16288196; PMID: 20805371). The full length of the PCDH21 protein is 120 kDa, the N-terminal soluble fragment is 95 kDa, and the C-terminal fragment is 25 kDa (PMID: 35066146; PMID: 18654668; PMID: 33964272).

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