Anticorps Polyclonal de lapin anti-PCDHB1

PCDHB1 Polyclonal Antibody for IP, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

IP, ELISA

Conjugaison

Non conjugué

N° de cat : 31966-1-AP

Synonymes

Protocadherin beta-1, Protocadherin Beta 1 , PCDH-beta-1

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Galerie de données de validation

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  IP experiment of mouse skeletal muscle using 31966-1-AP

  IP result of anti-PCDHB1 (IP:31966-1-AP, 4ug; Detection:31966-1-AP 1:500) with mouse skeletal muscle tissue lysate 1040 ug.

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  IP experiment of rat skeletal muscle using 31966-1-AP

  IP result of anti-PCDHB1 (IP:31966-1-AP, 4ug; Detection:31966-1-AP 1:500) with rat skeletal muscle tissue lysate 1800 ug.

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Applications testées

• Résultats positifs en IP: tissu de muscle squelettique de souris, tissu de muscle squelettique de rat

Dilution recommandée

• Immunoprécipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

31966-1-AP cible PCDHB1 dans les applications de IP, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PCDHB1 Protéine recombinante Ag35435
• Nom complet: protocadherin beta 1
• Poids moléculaire observé: 80 kDa
• Numéro d’acquisition GenBank: BC112096
• Symbole du gène: PCDHB1
• Identification du gène (NCBI): 29930
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

PCDHB1 (Protocadherin Beta 1) is a member of the protocadherin beta gene cluster, which belongs to the Cadherin superfamily and is expressed primarily in the nervous system. It encodes a cell adhesion protein containing six extracellular adhesion protein structural domains and a distinct cytoplasmic tail involved in the establishment and function of intercellular junctions. PCDHB1 plays an important role in neurodevelopment, and its aberrant expression has been associated with a variety of neurodevelopmental disorders, for example, PCDHB1 expression is upregulated in the brains of patients with Rett syndrome, which may be related to the neuropathological features of the disease. In addition, members of the PCDHB1 gene cluster are involved in neuronal self-recognition, avoidance, and connection establishment with other neurons.

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