Anticorps Polyclonal de lapin anti-PCDHB1

PCDHB1 Polyclonal Antibody for IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31966-1-PBS

Synonymes

Protocadherin beta-1, Protocadherin Beta 1 , PCDH-beta-1

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Galerie de données de validation

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  IP experiment of mouse skeletal muscle using 31966-1-AP (same clone as 31966-1-PBS)

  IP result of anti-PCDHB1 (IP:31966-1-AP, 4ug; Detection:31966-1-AP 1:500) with mouse skeletal muscle tissue lysate 1040 ug. This data was developed using the same antibody clone with 31966-1-PBS in a different storage buffer formulation.

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  IP experiment of rat skeletal muscle using 31966-1-AP (same clone as 31966-1-PBS)

  IP result of anti-PCDHB1 (IP:31966-1-AP, 4ug; Detection:31966-1-AP 1:500) with rat skeletal muscle tissue lysate 1800 ug. This data was developed using the same antibody clone with 31966-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31966-1-PBS cible PCDHB1 dans les applications de IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PCDHB1 Protéine recombinante Ag35435
• Nom complet: protocadherin beta 1
• Poids moléculaire observé: 80 kDa
• Numéro d’acquisition GenBank: BC112096
• Symbole du gène: PCDHB1
• Identification du gène (NCBI): 29930
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PCDHB1 (Protocadherin Beta 1) is a member of the protocadherin beta gene cluster, which belongs to the Cadherin superfamily and is expressed primarily in the nervous system. It encodes a cell adhesion protein containing six extracellular adhesion protein structural domains and a distinct cytoplasmic tail involved in the establishment and function of intercellular junctions. PCDHB1 plays an important role in neurodevelopment, and its aberrant expression has been associated with a variety of neurodevelopmental disorders, for example, PCDHB1 expression is upregulated in the brains of patients with Rett syndrome, which may be related to the neuropathological features of the disease. In addition, members of the PCDHB1 gene cluster are involved in neuronal self-recognition, avoidance, and connection establishment with other neurons.

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