Anticorps Polyclonal de lapin anti-PCDHGC5

PCDHGC5 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 23848-1-PBS

Synonymes

Protocadherin gamma-C5, PCDHGC, PCDH-gamma-C5

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Galerie de données de validation

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  IHC staining of human lung cancer using 23848-1-AP (same clone as 23848-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 23848-1-AP (PCDHGC5 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23848-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 23848-1-AP (same clone as 23848-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 23848-1-AP (PCDHGC5 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23848-1-PBS in a different storage buffer formulation.

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Informations sur le produit

23848-1-PBS cible PCDHGC5 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PCDHGC5 Protéine recombinante Ag20867
• Nom complet: protocadherin gamma subfamily C, 5
• Masse moléculaire calculée: 581aa,65 kDa; 944aa,102 kDa
• Numéro d’acquisition GenBank: BC112081
• Symbole du gène: PCDHGC5
• Identification du gène (NCBI): 56097
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). The protocadherin subfamily can be further subdivided into three groups: the clustered protocadherins, comprising α-, β- and γ-protocadherins; δ-protocadherins; and others, many of which are solitary (PMID: 17133224). Disruption of the γ-protocadherins locus causes neonatal lethality, and Pcdhgc3, Pcdhgc4, and Pcdhgc5 are essential for the observed lethality.

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