Anticorps Polyclonal de lapin anti-PCSK1

PCSK1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 28219-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 28219-1-AP (same clone as 28219-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 28219-1-AP (PCSK1 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28219-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas using 28219-1-AP (same clone as 28219-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 28219-1-AP (PCSK1 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28219-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas using 28219-1-AP (same clone as 28219-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 28219-1-AP (PCSK1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28219-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse pancreas using 28219-1-AP (same clone as 28219-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue slide using 28219-1-AP (PCSK1 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28219-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse pancreas using 28219-1-AP (same clone as 28219-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue slide using 28219-1-AP (PCSK1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28219-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 28219-1-AP (same clone as 28219-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28219-1-AP (PCSK1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28219-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 28219-1-AP (same clone as 28219-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28219-1-AP (PCSK1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28219-1-PBS in a different storage buffer formulation.

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Informations sur le produit

28219-1-PBS cible PCSK1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PCSK1 Protéine recombinante Ag28203
• Nom complet: proprotein convertase subtilisin/kexin type 1
• Masse moléculaire calculée: 753 aa, 84 kDa
• Poids moléculaire observé: 66 kDa
• Numéro d’acquisition GenBank: BC130295
• Symbole du gène: PCSK1
• Identification du gène (NCBI): 5122
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PC1/3, encoded by the gene PCSK1, is synthesized in the endoplasmic reticulum (ER) as an inactive 94 kDa zymogen, where it is rapidly cleaved into a partially active 87-kDa precursor. When this protein reaches the secretory granules, the maturation process continues to generate a 74 kDa species and ends with further cleavage to a fully active, although enzymatically unstable, 66 kDa protein.

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