Anticorps Recombinant de lapin anti-PD-L2/CD273

PD-L2/CD273 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

FITC Plus Fluorescent Dye

CloneNo.

241728D8

N° de cat : FITC-98241

Synonymes

PD-L2/B7-DC, 241728D8, B7dc, B7-DC, Btdc

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Galerie de données de validation

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  FC experiment of mouse splenocytes using FITC-98241

  1x10^6 untreated or GM-CSF treated mouse splenocytes were surface stained with APC Anti-Mouse CD11c and 0.25 ug FITC Plus Anti-Mouse PD-L2/CD273 Rabbit RecAb (FITC-98241, Clone: 241728D8). Cells were not fixed.

• 

  FC experiment of mouse splenocytes using FITC-98241

  1x10^6 GM-CSF treated mouse splenocytes were surface stained with 0.25 ug FITC Plus Anti-Mouse PD-L2/CD273 Rabbit RecAb (FITC-98241, Clone: 241728D8) (red) or FITC Plus Rabbit IgG Isotype Control RecAb (FITC-98136, Clone: 240953C9) (blue). 1x10^6 untreated mouse splenocytes were surface stained with 0.25 ug FITC Plus Anti-Mouse PD-L2/CD273 Rabbit RecAb (FITC-98241, Clone: 241728D8) (black, dashed). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: GM-CSF treated mouse splenocytes,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

FITC-98241 cible PD-L2/CD273 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: PD-L2/CD273 Protéine recombinante Eg1842
• Nom complet: programmed cell death 1 ligand 2
• Masse moléculaire calculée: 28kDa
• Numéro d’acquisition GenBank: NM_021396.2
• Symbole du gène: Pdcd1lg2
• Identification du gène (NCBI): 58205
• Conjugaison: FITC Plus Fluorescent Dye
• Excitation/Emission maxima wavelengths: 495 nm / 524 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Programmed cell death ligand 2 (PD-L2, also known as CD273, or B7-DC), is one of the B7 family molecules which are type I transmembrane proteins belonging to the immunoglobulin superfamily. PD-L2 was identified both by its homology to PD-L1 and by analysis of genes differentially expressed in libraries generated from dendritic cells (DC) and activated macrophages (PMID: 14515254). PD-L2 is a second ligand for PD-1, a costimulatory molecule that plays an inhibitory role in regulating T cell activation in the periphery.

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