Anticorps Polyclonal de lapin anti-PDCD11

PDCD11 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31405-1-PBS

Synonymes

programmed cell death 11, NFBP, NF kappa B binding protein, KIAA0185, ALG4

---

Galerie de données de validation

• 

  WB analysis using 31405-1-AP (same clone as 31405-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31405-1-AP (PDCD11 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31405-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

31405-1-PBS cible PDCD11 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PDCD11 Protéine recombinante Ag35402
• Nom complet: programmed cell death 11
• Poids moléculaire observé: 209 kDa
• Numéro d’acquisition GenBank: BC049838
• Symbole du gène: PDCD11
• Identification du gène (NCBI): 22984
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PDCD11, also known as ALG-4, RRP5, or NFBP, possesses a series of S1 RNA-binding domains in the N-terminus with approximately 1,400 amino acids, followed by a tetratricopeptide repeat (TPR) domain in the C-terminus. Through S1 N-terminal domains, PDCD11 interacts with pre-rRNA to coordinate rRNA processing and assembly in the nucleolus. It also binds to Exonuclease-1 and upregulates Fas to induce cell apoptosis. Recently, PDCD11 was proved to interact with NF-κB subunits to suppress the expression of inflammatory cytokines and activate the TGFβ1 pathway, thereby modulating microglia differentiation during zebrafish development.(PMID: 38062028)

{{ptg:RelatedPrimaryAntibodies}}