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Anticorps Polyclonal de lapin anti-PDE1C

PDE1C Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13785-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of human heart tissue using PDE1C Polyclonal antibody (13785-1-AP)

    WB analysis of human heart using 13785-1-AP (same clone as 13785-1-PBS)

    human heart tissue were subjected to SDS PAGE followed by western blot with 13785-1-AP (PDE1C antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13785-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of mouse heart tissue using PDE1C Polyclonal antibody (13785-1-AP)

    IP experiment of mouse heart using 13785-1-AP (same clone as 13785-1-PBS)

    IP result of anti-PDE1C (IP:13785-1-AP, 4ug; Detection:13785-1-AP 1:500) with mouse heart tissue lysate 4000ug. This data was developed using the same antibody clone with 13785-1-PBS in a different storage buffer formulation.

Informations sur le produit

13785-1-PBS cible PDE1C dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène PDE1C Protéine recombinante Ag4798
Nom complet phosphodiesterase 1C, calmodulin-dependent 70kDa
Masse moléculaire calculée 634 aa, 72 kDa
Poids moléculaire observé 68 kDa
Numéro d’acquisition GenBankBC022525
Symbole du gène PDE1C
Identification du gène (NCBI) 5137
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. PDE1C, is calmodulin-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex. Expression of PDE1C may be an important component in signal transduction pathways mediated by calcium that permit cell cycle traverse and proliferation(PMID:9366577). It has 2 isoforms produced by alternative splicing.

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