Anticorps Recombinant de lapin anti-PDE6D

• Phare
• Validé par KD/KO

PDE6D Recombinant Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

230546H1

N° de cat : 83503-1-PBS

Synonymes

PDED, 230546H1

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Galerie de données de validation

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  WB analysis using 83503-1-RR (same clone as 83503-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83503-1-RR (PDE6D antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83503-1-PBS in a different storage buffer formulation.

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  WB analysis of HeLa using 83503-1-RR (same clone as 83503-1-PBS)

  WB result of PDE6D antibody (83503-1-RR; 1:4000; incubated at room temperature for 1.5 hours) with sh-Control and sh-PDE6D transfected HeLa cells. This data was developed using the same antibody clone with 83503-1-PBS in a different storage buffer formulation.

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Informations sur le produit

83503-1-PBS cible PDE6D dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: PDE6D Protéine recombinante Ag29563
• Nom complet: phosphodiesterase 6D, cGMP-specific, rod, delta
• Masse moléculaire calculée: 17 KDa
• Poids moléculaire observé: 14-17 kDa
• Numéro d’acquisition GenBank: NM_002601
• Symbole du gène: PDE6D
• Identification du gène (NCBI): 5147
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PDE6D, also known as PDED, belongs to the PDE6D/unc-119 family. PDE6D is a ubiquitously expressed prenyl-binding protein. By binding to prenyl moieties, PDE6D mediates the shuttling of prenylated proteins between membranes. Thereby, it regulates the membrane association of Ras and Rap GTPases (PMID: 36672247). In addition, research has shown that PDE6D is overexpressed in liver cancer and correlated with tumor stages, grading, and ERK activation (PMID: 30901922). The calculated molecular weight of PDE6D is 17 kDa.

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