Anticorps Recombinant de lapin anti-PDGFR alpha/CD140a

PDGFR alpha/CD140a Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242025B3

N° de cat : 98256-1-PBS

Synonymes

EC:2.7.10.1, CD140a, CD140 antigen-like family member A, Alpha-type platelet-derived growth factor receptor, Alpha platelet-derived growth factor receptor

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Galerie de données de validation

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  FC experiment of NIH/3T3 using 98256-1-RR (same clone as 98256-1-PBS)

  1x10^6 NIH/3T3 cells were surface stained with 0.25 ug Anti-Mouse PDGFR alpha/CD140a Rabbit Recombinant Antibody (98256-1-RR, Clone: 242025B3) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (red), or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (blue). Cells were not fixed. This data was developed using the same antibody clone with 98256-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98256-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98256-1-RR against Mouse PDGFR alpha/CD140a were performed. The affinity constant is below 1 pM.

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Informations sur le produit

98256-1-PBS cible PDGFR alpha/CD140a dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: platelet derived growth factor receptor, alpha polypeptide
• Masse moléculaire calculée: 123kDa
• Numéro d’acquisition GenBank: NM_001083316.2
• Symbole du gène: Pdgfra
• Identification du gène (NCBI): 18595
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Platelet-derived growth factor receptor alpha (PDGFR alpha, also known as CD140a) is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRA is implicated in the regulation of embryonic development, tumorigenesis, cell proliferation, survival, and chemotaxis. Mutations in the PDGFRA gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

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