Anticorps Recombinant de lapin anti-PDIR

PDIR Recombinant Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242971D11

N° de cat : 85599-4-PBS

Synonymes

PDIA5, EC:5.3.4.1, Protein disulfide isomerase A5, Protein disulfide isomerase-related protein, Protein disulfide-isomerase A5

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Galerie de données de validation

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  WB analysis using 85599-4-RR (same clone as 85599-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85599-4-RR (PDIA5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85599-4-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 85599-4-RR (same clone as 85599-4-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 85599-4-RR (PDIR antibody) at dilution of 1:4000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85599-4-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 85599-4-RR (same clone as 85599-4-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 85599-4-RR (PDIR antibody) at dilution of 1:4000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85599-4-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 85599-4-RR

  Biolayer interferometry (BLl) kinetic assays of 85599-4-RR against Human PDIR were performed. The affinity constant is below 1 pM.

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Informations sur le produit

85599-4-PBS cible PDIR dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: PDIR Protéine recombinante Ag31479
• Nom complet: protein disulfide isomerase family A, member 5
• Masse moléculaire calculée: 60 kDa
• Poids moléculaire observé: 60 kDa
• Numéro d’acquisition GenBank: BC001625
• Symbole du gène: PDIR
• Identification du gène (NCBI): 10954
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PDIR(Protein disulfide isomerase-related protein), also known as PDIA5 (Protein Disulfide Isomerase Family A Member 5), is a member of the PDI gene family and also exhibits chaperone-like activity. PDIR protein is correlated with immune infiltration, which is highly expressed in glioma and participates in glioma progression(PMID: 33664747). PDIR contributes to disulfide bond rearrangement in ATF6α under stress conditions that necessary for ATF6α activation upon ER stress(PMID: 24636989).

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