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Anticorps Monoclonal anti-PDLIM5

PDLIM5 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgM

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1H9C9

N° de cat : 67651-1-PBS

Synonymes

ENH, ENH1, Enigma homolog, L9, LIM, PDLIM5, PDZ and LIM domain 5, PDZ and LIM domain protein 5

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using PDLIM5 Monoclonal antibody (67651-1-Ig)

    WB analysis using 67651-1-Ig (same clone as 67651-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67651-1-Ig (PDLIM5 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67651-1-PBS in a different storage buffer formulation.

Informations sur le produit

67651-1-PBS cible PDLIM5 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Mouse / IgM
Clonalité Monoclonal
Type Anticorps
Immunogène PDLIM5 Protéine recombinante Ag25059
Nom complet PDZ and LIM domain 5
Masse moléculaire calculée 64 kDa
Poids moléculaire observé 63-69 kDa
Numéro d’acquisition GenBankBC008741
Symbole du gène PDLIM5
Identification du gène (NCBI) 10611
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Précipitation des euglobulines
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PDLIM5 (PDZ and LIM domain 5), formerly known as enigma homolog (ENH), is a cytoplasmic protein containing PDZ domain and LIM domain at N terminus and C terminus, respectively. PDLIM5 gene generates several splicing variants, EZH1 to EZH4. The long isoform, ENH1, is widely expressed in various tissues including heart, brain, spleen, liver and kidney. In comparison, shorter isoforms that lack the LIM motifs are expressed in cardiac (ENH3) and skeletal muscle (ENH2, ENH3, and ENH4). ENH1 is essential for differentiation of striated muscles through interaction with other proteins. In addition, PDLIM5 is also involved in mood disorders, such as schizophrenia, bipolar disorder, and major depression.

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