Anticorps Monoclonal anti-PDXDC1

PDXDC1 Monoclonal Antibody for WB, IF/ICC, ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, porc, rat, souris

Applications

WB, IF/ICC, ELISA

Conjugaison

Non conjugué

CloneNo.

1E6E2

N° de cat : 68278-1-PBS

Synonymes

KIAA0251, LP8165, PDXDC1

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Galerie de données de validation

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  WB analysis using 68278-1-Ig (same clone as 68278-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68278-1-Ig (PDXDC1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Alpha Tubulin Monoclonal antibody (HRP-66031) as loading control. This data was developed using the same antibody clone with 68278-1-PBS in a different storage buffer formulation.

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  WB analysis using 68278-1-Ig (same clone as 68278-1-PBS)

  NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 68278-1-Ig (PDXDC1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Alpha Tubulin Monoclonal antibody (HRP-66031) as loading control. This data was developed using the same antibody clone with 68278-1-PBS in a different storage buffer formulation.

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  IF Staining of MCF-7 using 68278-1-Ig (same clone as 68278-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed MCF-7 cells using PDXDC1 antibody (68278-1-Ig, Clone: 1E6E2 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L), CL594-Phalloidin (red). This data was developed using the same antibody clone with 68278-1-PBS in a different storage buffer formulation.

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  IF Staining of MCF-7 using 68278-1-Ig (same clone as 68278-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed MCF-7 cells using PDXDC1 antibody (68278-1-Ig, Clone: 1E6E2 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 68278-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68278-1-PBS cible PDXDC1 dans les applications de WB, IF/ICC, ELISA et montre une réactivité avec des échantillons Humain, porc, rat, souris

• Réactivité: Humain, porc, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: PDXDC1 Protéine recombinante Ag15489
• Nom complet: pyridoxal-dependent decarboxylase domain containing 1
• Masse moléculaire calculée: 788 aa, 87 kDa
• Poids moléculaire observé: 87 kDa
• Numéro d’acquisition GenBank: BC033748
• Symbole du gène: PDXDC1
• Identification du gène (NCBI): 23042
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PDXDC1 (pyridoxal-dependent decarboxylase domain containing 1) is a putative enzyme that could metabolize catecholamine neurotransmitters (PMID:28485732). With prior evidence for involvement with glioblastoma from other previously reported experimental settings, and contains the lead single nucleotide polymorphism (rs3198697) from the linkage analysis of the chromosome 16 region (PMID:32644145). Moreover, PDXDC1 is involved in the catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound (PMID:29277971).

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