Anticorps Recombinant de lapin anti-PEA15

PEA15 Recombinant Antibody for IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241044H6

N° de cat : 83958-3-PBS

Synonymes

MAT1H, MAT1, HUMMAT1H, HMAT1, Astrocytic phosphoprotein PEA-15

---

Galerie de données de validation

• 

  IF Staining of A431 using 83958-3-RR (same clone as 83958-3-PBS)

  Immunofluorescent analysis of (4% PFA) fixed A431 cells using PEA15 antibody (83958-3-RR, Clone: 241044H6 ) at dilution of 1:250 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83958-3-PBS in a different storage buffer formulation.

• 

  IF Staining of A431 using 83958-3-RR (same clone as 83958-3-PBS)

  Immunofluorescent analysis of (4% PFA) fixed A431 cells using PEA15 antibody (83958-3-RR, Clone: 241044H6 ) at dilution of 1:500 and CoraLite®594-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-4). This data was developed using the same antibody clone with 83958-3-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 83958-3-RR

  Biolayer interferometry (BLl) kinetic assays of 83958-3-RR against Human PEA15 were performed. The affinity constant is 6.95 nM.

---

Informations sur le produit

83958-3-PBS cible PEA15 dans les applications de IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: PEA15 Protéine recombinante Ag13782
• Nom complet: phosphoprotein enriched in astrocytes 15
• Masse moléculaire calculée: 130 aa, 15 kDa
• Poids moléculaire observé: 15 kDa
• Numéro d’acquisition GenBank: BC002426
• Symbole du gène: PEA15
• Identification du gène (NCBI): 8682
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Phosphoprotein Enriched in Astrocytes 15 kDa (PEA15), also known as PED-15, is a small, death effector-domain (DED)-containing protein that was recently demonstrated to inhibit tumor necrosis factor-α-induced apoptosis and to reverse the inhibition of integrin activation due to H-Ras. PEA15 is a 15 kDa protein that is highly expressed in the nervous system with particularly high levels in astrocytes and neurons of the hippocampus. PEA15 is a cytoplasmic protein that sits at an important junction in intracellular signalling and can regulate diverse cellular processes, such as proliferation and apoptosis, dependent upon stimulation.

{{ptg:RelatedPrimaryAntibodies}}