Anticorps Recombinant de lapin anti-PEBP4

PEBP4 Recombinant Antibody for IF/ICC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IF/ICC, ELISA

Conjugaison

Non conjugué

CloneNo.

240547D8

N° de cat : 83589-5-RR

Synonymes

PEBP 4, hPEBP4, GWTM1933, CORK1, CORK 1

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Galerie de données de validation

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  IF Staining of A549 using 83589-5-RR

  Immunofluorescent analysis of (4% PFA) fixed A549 cells using PEBP4 antibody (83589-5-RR, Clone: 240547D8 ) at dilution of 1:250 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2).

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  Affinity and Kinetic Characterization of 83589-5-RR

  Biolayer interferometry (BLl) kinetic assays of 83589-5-RR against Human PEBP4 were performed. The affinity constant is below 1 pM.

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Applications testées

• Résultats positifs en IF/ICC: cellules A549,

Dilution recommandée

• Immunofluorescence (IF)/ICC: IF/ICC : 1:125-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

83589-5-RR cible PEBP4 dans les applications de IF/ICC, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: PEBP4 Protéine recombinante Ag9710
• Nom complet: phosphatidylethanolamine-binding protein 4
• Masse moléculaire calculée: 223 aa, 25 kDa
• Numéro d’acquisition GenBank: BC020779
• Symbole du gène: PEBP4
• Identification du gène (NCBI): 157310
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

PEBP4 (Phosphatidylethanolamine binding protein 4) is a multifunctional protein that belongs to a small family (PEBP1-4) in mammalian cells. PEBP4 is evolutionally divergent from the other three forms that share almost 80% identity and more than 90% similarity, suggesting that PEBP4 is functionally different from other forms. At cellular levels, it has been shown that the knockdown of PEBP4 in cancer cells suppresses cell proliferation, migration, and invasion, leading to their apoptosis. In contrast, overexpression of PEBP4 induces opposite changes and confers resistance to chemotherapy and radiotherapy (PMID: 35955931).

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