Anticorps Monoclonal anti-Serpin F1/PEDF

Serpin F1/PEDF Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, porc

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2C5C8

N° de cat : 66554-1-PBS

Synonymes

PEDF, PIG35, 2C5C8, Cell proliferation-inducing gene 35 protein, EPC 1

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Galerie de données de validation

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  WB analysis of human plasma using 66554-1-Ig (same clone as 66554-1-PBS)

  human plasma were subjected to SDS PAGE followed by western blot with 66554-1-Ig (PEDF antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66554-1-PBS in a different storage buffer formulation.

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  WB analysis of pig plasma using 66554-1-Ig (same clone as 66554-1-PBS)

  pig plasma were subjected to SDS PAGE followed by western blot with 66554-1-Ig (PEDF antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66554-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human blood using 66554-1-Ig (same clone as 66554-1-PBS)

  human blood were subjected to SDS PAGE followed by western blot with 66554-1-Ig (PEDF antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66554-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66554-1-PBS cible Serpin F1/PEDF dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc

• Réactivité: Humain, porc
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Serpin F1/PEDF Protéine recombinante Ag26660
• Nom complet: serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
• Masse moléculaire calculée: 418 aa, 46 kDa
• Poids moléculaire observé: 46-50 kDa
• Numéro d’acquisition GenBank: BC013984
• Symbole du gène: PEDF
• Identification du gène (NCBI): 5176
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PEDF also known as serpin F1 (SERPINF1), is a multifunctional secreted protein that has anti-angiogenic, anti-tumorigenic, and neurotrophic functionsis. It is an approximately 50-kDa secreted protein that is widely expressed, including by osteoblasts and osteoclasts. PEDF is also one of the most abundant secretory products of adipocytes, and circulating concentrations of PEDF correlate positively with body fat mass and INS resistance. PEDF is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI.

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