Anticorps Polyclonal de lapin anti-PEG3

PEG3 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 23569-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 23569-1-AP (same clone as 23569-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 23569-1-AP (PEG3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23569-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 23569-1-AP (same clone as 23569-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 23569-1-AP (PEG3 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23569-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 23569-1-AP (same clone as 23569-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 23569-1-AP (PEG3 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23569-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 23569-1-AP (same clone as 23569-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 23569-1-AP (PEG3 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23569-1-PBS in a different storage buffer formulation.

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Informations sur le produit

23569-1-PBS cible PEG3 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PEG3 Protéine recombinante Ag20132
• Nom complet: paternally expressed 3
• Masse moléculaire calculée: 1588 aa, 181 kDa
• Poids moléculaire observé: 200-220 kDa
• Numéro d’acquisition GenBank: BC150272
• Symbole du gène: PEG3
• Identification du gène (NCBI): 5178
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Paternally expressed 3 (PEG3) was responsible for Kras/Erk- and mTOR-driven HCC (hepatocellular carcinoma) (PMID: 36451866). PEG3 can regulate the physiological processes related to energy homeostasis found in multiple tissues, such as the brain, testis, ovary, and placenta (PMID: 32729618). Epigenetic silencing and loss of imprinting of PEG3 are implicated in glioma tumorigenesis (PMID: 32231463).

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