Anticorps Recombinant de lapin anti-PEX1

PEX1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242994F11

N° de cat : 85429-4-PBS

Synonymes

EC:3.6.4.-, Peroxin 1, Peroxin-1, Peroxisomal ATPase PEX1, Peroxisome biogenesis factor 1

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Galerie de données de validation

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  WB analysis using 85429-4-RR (same clone as 85429-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85429-4-RR (PEX1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85429-4-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 85429-4-RR

  Biolayer interferometry (BLl) kinetic assays of 85429-4-RR against Human PEX1 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

85429-4-PBS cible PEX1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: PEX1 Protéine recombinante Ag4623
• Nom complet: peroxisomal biogenesis factor 1
• Masse moléculaire calculée: 1283 aa, 143 kDa
• Poids moléculaire observé: 143 kDa
• Numéro d’acquisition GenBank: BC035575
• Symbole du gène: PEX1
• Identification du gène (NCBI): 5189
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Peroxin (PEX) proteins generate and maintain peroxisomes. The peroxin-1 (PEX1) ATPase facilitates the recycling of the peroxisome matrix protein receptor PEX5 and is the most commonly affected peroxin in human peroxisome biogenesis disorders (PMID: 28600347).  PEX1 and PEX6 are the only members of the AAA family (for ATPases associated with diverse cellular) activities implicated in peroxisome biogenesis and are closely related to p97, which functions in endoplasmic reticulum-associated protein degradation to retrotranslocate endoplasmic reticulum proteins to the cytosol (PMID: 9695811; 11740563).

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