Anticorps Recombinant de lapin anti-PEX3

PEX3 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251383E9

N° de cat : 86594-1-PBS

Synonymes

Peroxin 3, Peroxin-3, PEX

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Galerie de données de validation

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  WB analysis using 86594-1-RR (same clone as 86594-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86594-1-RR (PEX3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86594-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 86594-1-RR (same clone as 86594-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86594-1-RR (PEX3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86594-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 86594-1-RR

  Biolayer interferometry (BLl) kinetic assays of 86594-1-RR against Human PEX3 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

86594-1-PBS cible PEX3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: PEX3 Protéine recombinante Ag31516
• Nom complet: peroxisomal biogenesis factor 3
• Masse moléculaire calculée: 42 kDa
• Poids moléculaire observé: 42 kDa
• Numéro d’acquisition GenBank: BC014551
• Symbole du gène: PEX3
• Identification du gène (NCBI): 8504
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. Peroxin 3, also known as PEX3 (peroxisomal biogenesis factor 3) or TRG18, is a 373 amino acid multi-pass membrane protein that anchored in the peroxisomal membrane and essential for peroxisome biogenesis and integrity. Additionally, Peroxin 3 acts as a docking factor for Peroxin 19 and is required for the import of peroxisomal proteins. Defects in the gene encoding Peroxin 3 are the cause of peroxisome biogenesis disorder complementation group 12 (PBD-CG12) and Zellweger syndrome (ZwS), both of which arise from a failure of peroxisomal protein import.

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