Anticorps Monoclonal anti-PEX5

• Phare
• Validé par KD/KO

PEX5 Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, porc, rat

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1C2C3

N° de cat : 66309-1-PBS

Synonymes

Cell and organelle markers, Peroxin 5, Peroxisome Marker, Peroxisome receptor 1, PEX5, PTS1 BP, PTS1 receptor, PTS1R, PXR1

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Galerie de données de validation

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  WB analysis of HEK-293 using 66309-1-Ig (same clone as 66309-1-PBS)

  WB result of PEX5 antibody (66309-1-Ig; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-PEX5 transfected HEK-293 cells. This data was developed using the same antibody clone with 66309-1-PBS in a different storage buffer formulation.

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  WB analysis of pig brain using 66309-1-Ig (same clone as 66309-1-PBS)

  pig brain tissue were subjected to SDS PAGE followed by western blot with 66309-1-Ig (PEX5 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66309-1-PBS in a different storage buffer formulation.

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  WB analysis of fetal human brain using 66309-1-Ig (same clone as 66309-1-PBS)

  fetal human brain tissue were subjected to SDS PAGE followed by western blot with 66309-1-Ig (PEX5 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66309-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 66309-1-Ig (same clone as 66309-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 66309-1-Ig (PEX5 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 66309-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 66309-1-Ig (same clone as 66309-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 66309-1-Ig (PEX5 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 66309-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 66309-1-Ig (same clone as 66309-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66309-1-Ig (PEX5 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 66309-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 66309-1-Ig (same clone as 66309-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66309-1-Ig (PEX5 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 66309-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66309-1-PBS cible PEX5 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc, rat

• Réactivité: Humain, porc, rat
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: PEX5 Protéine recombinante Ag3268
• Nom complet: peroxisomal biogenesis factor 5
• Masse moléculaire calculée: 631 aa, 70 kDa
• Poids moléculaire observé: 70-80 kDa
• Numéro d’acquisition GenBank: BC010621
• Symbole du gène: PEX5
• Identification du gène (NCBI): 5830
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The peroxisomal targeting signal type1 (PTS1) receptor, PEX5, is one member of peroxins (PEXs) which are proteins required for peroxisome assembly. PEX5 and PEX7 function as receptors that recognize PTS1- and PTS2- containing proteins, respectively, and PEX5 binds PTS1 through its C-terminal 40-kDa tetratricopeptide repeat domain. It is a predominantly cytoplasmic, partly peroxisomal protein that appears to shuttle between these compartments as it mediates the import of PTS1-containing proteins. PEX5 has been reported to interact with PEX10, PEX12, PEX13, and PEX14. Defects in PEX5 are a cause of Zellweger syndrome (ZWS), which is a lethal peroxisome biogenesis disorder.

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