Anticorps Polyclonal de lapin anti-PFKFB2

PFKFB2 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 17838-1-PBS

Synonymes

Fructose-2,6-bisphosphatase, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2, 6-phosphofructo-2-kinase, 6PF-2-K/Fru-2,6-P2ase heart-type isozyme, 6PF-2-K/Fru-2,6-P2ase 2

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Galerie de données de validation

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  WB analysis using 17838-1-AP (same clone as 17838-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17838-1-AP (PFKFB2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17838-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse retina using 17838-1-AP (same clone as 17838-1-PBS)

  mouse retina tissue were subjected to SDS PAGE followed by western blot with 17838-1-AP (PFKFB2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17838-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17838-1-PBS cible PFKFB2 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PFKFB2 Protéine recombinante Ag12181
• Nom complet: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
• Masse moléculaire calculée: 505 aa, 58 kDa
• Poids moléculaire observé: 55 kDa
• Numéro d’acquisition GenBank: BC075076
• Symbole du gène: PFKFB2
• Identification du gène (NCBI): 5208
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PFKFB2(6-Phosphofructo-2-kinase/fructose 2,6-bisphosphatase 2) is also named as PFK-2/FBPase-2, which is a bifunctional enzyme responsible for the synthesis and breakdown of Fru-2,6-P2 in the regulation of glycolysis(PMID:10095107). In the C-terminal section, it belongs to the phosphoglycerate mutase family. The enzyme is a dimer of identical subunits, each composed of 505 amino acids and containing three discrete domains(PMID: 2552438). It has 2 isoforms produced by alternative splicing.

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