Anticorps Polyclonal de lapin anti-PGAM2-Specific

PGAM2-Specific Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25518-1-PBS

Synonymes

PGAM2, BPG dependent PGAM 2, BPG-dependent PGAM 2, EC:5.4.2.11, Muscle-specific phosphoglycerate mutase

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Galerie de données de validation

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  WB analysis of mouse testis using 25518-1-AP (same clone as 25518-1-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 25518-1-AP (PGAM2 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25518-1-PBS in a different storage buffer formulation.

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Informations sur le produit

25518-1-PBS cible PGAM2-Specific dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: phosphoglycerate mutase 2 (muscle)
• Masse moléculaire calculée: 28 kDa
• Poids moléculaire observé: 29 kDa
• Numéro d’acquisition GenBank: NM_000290
• Symbole du gène: PGAM2
• Identification du gène (NCBI): 5224
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Phosphoglycerate mutase (PGAM), an important enzyme in the glycolytic pathway, catalyzes the transfer of a phosphate group between the 2 and the 3 positions of glyceric acid. The muscle-specific isoform (type M, PGAM2) of phosphoglycerate mutase (PGAM) is a housekeeping enzyme and it catalyzes the conversion of 3-phosphoglycerate into 2-phosphoglycerate in the glycolysis process to release energy. It is encoded by the Pgam2 gene. In addition, it is demonstrated that PGAM2 locates both in cytoplasm and nuclei, and takes part in the glycometabolism process of cytoplasm and nuclei(PMID: 18499067). Defects in PGAM2 are the cause of glycogen storage disease type 10 (GSD10). This antibody is specific for PGAM2.

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