Anticorps Monoclonal anti-PTGDS

PTGDS Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain, Lapin, porc, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2D6E7

N° de cat : 68783-3-PBS

Synonymes

Lipocalin-type prostaglandin-D synthase, Glutathione-independent PGD synthase, EC:5.3.99.2, Cerebrin-28, Beta-trace protein

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Galerie de données de validation

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  WB analysis using 68783-3-Ig (same clone as 68783-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68783-3-Ig (PGDS antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68783-3-PBS in a different storage buffer formulation.

• 

  WB analysis using 68783-3-Ig (same clone as 68783-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68783-3-Ig (PGDS antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68783-3-PBS in a different storage buffer formulation.

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Informations sur le produit

68783-3-PBS cible PTGDS dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, Lapin, porc, rat, souris

• Réactivité: Humain, Lapin, porc, rat, souris
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: PTGDS Protéine recombinante Ag34483
• Nom complet: prostaglandin D2 synthase 21kDa (brain)
• Masse moléculaire calculée: 21 kDa
• Poids moléculaire observé: 28 kDa
• Numéro d’acquisition GenBank: BC005939
• Symbole du gène: PTGDS
• Identification du gène (NCBI): 5730
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Glycoprotein prostaglandin D2 synthase (PTGDS), also known as L-PGDS, PGDS, and LPGDS, is a member of the lipocalin superfamily and plays dual roles in prostaglandins metabolism and lipid transport (PMID: 34743203). PTGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PTGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. PTGDS is abundantly expressed in the brain and heart and has also been found in testis, prostate, kidney, spleen and leukocytes. It can be found as a collection of monomeric glycoforms with molecular weights in the 27-34 kDa range (PMID: 32430846).

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