Anticorps Recombinant de lapin anti-HPGDS

HPGDS Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242980B8

N° de cat : 85446-2-PBS

Synonymes

EC:2.5.1.18, EC:5.3.99.2, Glutathione S transferase, Glutathione S-transferase, Glutathione-dependent PGD synthase

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Galerie de données de validation

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  WB analysis of human placenta using 85446-2-RR (same clone as 85446-2-PBS)

  human placenta tissue were subjected to SDS PAGE followed by western blot with 85446-2-RR (HPGDS antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85446-2-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 85446-2-RR

  Biolayer interferometry (BLl) kinetic assays of 85446-2-RR against Human HPGDS were performed. The affinity constant is 0.168 nM.

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Informations sur le produit

85446-2-PBS cible HPGDS dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: HPGDS Protéine recombinante Ag18290
• Nom complet: prostaglandin D2 synthase, hematopoietic
• Masse moléculaire calculée: 199 aa, 23 kDa
• Poids moléculaire observé: 26 kDa, 52 kDa
• Numéro d’acquisition GenBank: BC020734
• Symbole du gène: HPGDS
• Identification du gène (NCBI): 27306
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Hematopoietic PGD synthase (HPGDS), one of the PGD2 synthases, is distributed in the cytoplasm of mast cells and Th2 cells and catalyzes PGD2 production during inflammation and allergic reactions. HPGDS belongs to the gene family of σ-type glutathione S-transferase (GST). Like other GSTs, it exists as a homodimer in vivo with a molecular weight of approximately 52 kDa (PMID: 38339125).

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