Anticorps Recombinant de lapin anti-PGLYRP1

PGLYRP1 Recombinant Antibody for WB, IHC, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

243004F5

N° de cat : 85610-4-PBS

Synonymes

PGLYRP, PGRP, PGRP S, PGRPS, PGRP-S

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Galerie de données de validation

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  WB analysis of human urine using 85610-4-RR (same clone as 85610-4-PBS)

  human urine sample were subjected to SDS PAGE followed by western blot with 85610-4-RR (PGLYRP1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85610-4-PBS in a different storage buffer formulation.

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  IHC staining of mouse spleen using 85610-4-RR (same clone as 85610-4-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse spleen tissue slide using 85610-4-RR (PGLYRP1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85610-4-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse spleen using 85610-4-RR (same clone as 85610-4-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse spleen tissue slide using 85610-4-RR (PGLYRP1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85610-4-PBS in a different storage buffer formulation.

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  IF Staining of mouse spleen using 85610-4-RR (same clone as 85610-4-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse spleen tissue using PGLYRP1 antibody (85610-4-RR, Clone: 243004F5 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85610-4-PBS in a different storage buffer formulation.

• 

  IF Staining of mouse spleen using 85610-4-RR (same clone as 85610-4-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse spleen tissue using PGLYRP1 antibody (85610-4-RR, Clone: 243004F5 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85610-4-PBS in a different storage buffer formulation.

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Informations sur le produit

85610-4-PBS cible PGLYRP1 dans les applications de WB, IHC, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: PGLYRP1 Protéine recombinante Eg3122
• Nom complet: peptidoglycan recognition protein 1
• Masse moléculaire calculée: 22 kDa
• Poids moléculaire observé: 25 kDa
• Numéro d’acquisition GenBank: NM_005091.2
• Symbole du gène: PGLYRP1
• Identification du gène (NCBI): 8993
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Peptidoglycan recognition protein 1 (PGLYRP1, also known as PGRP-S) belongs to a family of evolutionary conserved innate immunity proteins, which in mammals also include PGLYRP2, PGLYRP3, and PGLYRP4 (PMID: 17275309; 20418257). PGLYRP1 is highly expressed in polymorphonuclear leukocytes and to a lower extent in many non-immune cells (PMID: 20418257). It recognizes bacterial peptidoglycan and functions in antibacterial immunity and inflammation (PMID: 20418257). PGLYRP1 has been identified as a ligand for TREM-1 (PMID: 25595774).

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