Anticorps Recombinant de lapin anti-PGM2L1

PGM2L1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250849G1

N° de cat : 86209-1-PBS

Synonymes

BM32A, EC:2.7.1.106, Glucose 1,6-bisphosphate synthase, Phosphoglucomutase-2-like 1, PMMLP

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Galerie de données de validation

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  WB analysis using 86209-1-RR (same clone as 86209-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86209-1-RR (PGM2L1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86209-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 86209-1-RR

  Biolayer interferometry (BLl) kinetic assays of 86209-1-RR against Human PGM2L1 were performed. The affinity constant is 0.189 nM.

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Informations sur le produit

86209-1-PBS cible PGM2L1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: PGM2L1 Protéine recombinante Ag5019
• Nom complet: phosphoglucomutase 2-like 1
• Masse moléculaire calculée: 70 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC059360
• Symbole du gène: PGM2L1
• Identification du gène (NCBI): 283209
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PGM2L1 (Phosphoglucomutase 2 Like 1) is an enzyme-like protein involved in carbohydrate metabolism. PGM2L1 catalyzes the formation of G16BP by using the glycolytic intermediate 1,3-bisphosphoglycerate as a phosphate donor and glucose-1-phosphate or glucose-6-phosphate as a phosphate acceptor. PGM2L1 plays a crucial role in glycogen metabolism, glycolysis, and gluconeogenesis as a key enzyme, and increasing evidence links its function to cancer metabolism and progression. While PGM2 has a wide tissue distribution, PGM2L1 is highly expressed in the brain, accounting for the elevated concentrations of glucose-1,6-bisphosphate found there (PMID: 33979636, PMID: 40027181).

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