Anticorps Recombinant de lapin anti-PI3 Kinase p110 Alpha

PI3 Kinase p110 Alpha Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1B4

N° de cat : 82796-4-PBS

Synonymes

PI3K p110(alpha), PIK3CA, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha, p110 alpha

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Galerie de données de validation

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  WB analysis using 82796-4-RR (same clone as 82796-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 82796-4-RR (PIK3CA antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82796-4-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 82796-4-RR

  Biolayer interferometry (BLl) kinetic assays of 82796-4-RR against Human PI3 Kinase p110 Alpha were performed. The affinity constant is 0.639 nM.

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Informations sur le produit

82796-4-PBS cible PI3 Kinase p110 Alpha dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: PI3 Kinase p110 Alpha Protéine recombinante Ag16586
• Nom complet: phosphoinositide-3-kinase, catalytic, alpha polypeptide
• Masse moléculaire calculée: 1068 aa, 124 kDa
• Poids moléculaire observé: 110 kDa
• Numéro d’acquisition GenBank: BC113601
• Symbole du gène: PIK3CA
• Identification du gène (NCBI): 5290
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PIK3CA belongs to the PI3/PI4-kinase family. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. Defects in PIK3CA are associated with colorectal cancer (CRC). Defects in PIK3CA are associated with breast cancer. Defects in PIK3CA are associated with ovarian cancer. Defects in PIK3CA may underlie hepatocellular carcinoma (HCC). Defects in PIK3CA are a cause of keratosis seborrheic (KERSEB).

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