Anticorps Polyclonal de lapin anti-PITRM1

PITRM1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30674-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 30674-1-AP (same clone as 30674-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30674-1-AP (PITRM1 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30674-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 30674-1-AP (same clone as 30674-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 30674-1-AP (PITRM1 antibody) at dilution of 1:600 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30674-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 30674-1-AP (same clone as 30674-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 30674-1-AP (PITRM1 antibody) at dilution of 1:600 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30674-1-PBS in a different storage buffer formulation.

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Informations sur le produit

30674-1-PBS cible PITRM1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PITRM1 Protéine recombinante Ag30478
• Nom complet: pitrilysin metallopeptidase 1
• Masse moléculaire calculée: 60 kDa, 117 kDa
• Poids moléculaire observé: 110-120 kDa
• Numéro d’acquisition GenBank: BC001150
• Symbole du gène: PITRM1
• Identification du gène (NCBI): 10531
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PITRM1 (Presequence protease, mitochondrial) is a ATP-independent protease that degrades mitochondrial transit peptides after their cleavage.It is specific for peptides in the range of 10 to 65 residues.and able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease.It shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference(PMID:16849325).This protein has a calculated molecular mass of 117kD and it is expressed widely.

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