Anticorps Polyclonal de lapin anti-PKC Gamma

PKC Gamma Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 29208-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 29208-1-AP (same clone as 29208-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29208-1-AP (PKC Gamma antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29208-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse cerebellum using 29208-1-AP (same clone as 29208-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 29208-1-AP (PKC Gamma antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29208-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse cerebellum using 29208-1-AP (same clone as 29208-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 29208-1-AP (PKC Gamma antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29208-1-PBS in a different storage buffer formulation.

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Informations sur le produit

29208-1-PBS cible PKC Gamma dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PKC Gamma Protéine recombinante Ag25085
• Nom complet: protein kinase C, gamma
• Masse moléculaire calculée: 78 kDa
• Poids moléculaire observé: 78 kDa
• Numéro d’acquisition GenBank: BC047876
• Symbole du gène: PKC Gamma
• Identification du gène (NCBI): 5582
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC gamma is a neuron-specific member of the classical PKCs and is activated and translocated to subcellular regions as a result of various stimuli, including diacylglycerol synthesis, increased intracellular Ca(2+) and phorbol esters. Defects in this protein have been associated with spinocerebellar ataxia type 14 (SCA14), an autosomal dominant neurodegenerative disease.

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