Anticorps Recombinant de lapin anti-PLS3

PLS3 Recombinant Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250908B6

N° de cat : 86323-1-PBS

Synonymes

Plastin 3, Plastin-3, T plastin, T-fimbrin, T-plastin

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Galerie de données de validation

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  WB analysis using 86323-1-RR (same clone as 86323-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86323-1-RR (PLS3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86323-1-PBS in a different storage buffer formulation.

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  WB analysis using 86323-1-RR (same clone as 86323-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86323-1-RR (PLS3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86323-1-PBS in a different storage buffer formulation.

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  IHC staining of human skin cancer using 86323-1-RR (same clone as 86323-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 86323-1-RR (PLS3 antibody) at dilution of 1:500 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 86323-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skin cancer using 86323-1-RR (same clone as 86323-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 86323-1-RR (PLS3 antibody) at dilution of 1:500 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 86323-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86323-1-PBS cible PLS3 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: plastin 3 (T isoform)
• Masse moléculaire calculée: 71 kDa
• Poids moléculaire observé: 68 kDa
• Numéro d’acquisition GenBank: NM_005032
• Symbole du gène: PLS3
• Identification du gène (NCBI): 5358
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PLS3, also named T-plastin and Plastin-3, is an actin-bundling protein found in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia. It plays an important role in leukocyte function. L-plastin plays an important role in leukocyte function, and T-plastin is possibly involved in DNA repair. Both T- and L-plastin are implicated in several diseases, and L-plastin is considered to be a valuable marker for cancer (PMID: 15960882).

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