Anticorps Polyclonal de lapin anti-PLXDC2

PLXDC2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12285-1-PBS

Synonymes

UNQ2514/PRO6003, Tumor endothelial marker 7-related protein, TEM7R, Plexin domain-containing protein 2, plexin domain containing 2

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Galerie de données de validation

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  WB analysis of A431 using 12285-1-AP (same clone as 12285-1-PBS)

  A431 cells were subjected to SDS PAGE followed by western blot with 12285-1-AP (PLXDC2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12285-1-PBS in a different storage buffer formulation.

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  WB analysis using 12285-1-AP (same clone as 12285-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12285-1-AP (PLXDC2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12285-1-PBS in a different storage buffer formulation.

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  WB analysis of HeLa using 12285-1-AP (same clone as 12285-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 12285-1-AP (PLXDC2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12285-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 12285-1-AP (same clone as 12285-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 12285-1-AP (PLXDC2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12285-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 12285-1-AP (same clone as 12285-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 12285-1-AP (PLXDC2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12285-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 12285-1-AP (same clone as 12285-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 12285-1-AP (PLXDC2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12285-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 12285-1-AP (same clone as 12285-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 12285-1-AP (PLXDC2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12285-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12285-1-PBS cible PLXDC2 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PLXDC2 Protéine recombinante Ag2940
• Nom complet: plexin domain containing 2
• Masse moléculaire calculée: 480 aa, 54 kDa
• Poids moléculaire observé: 60 kDa
• Numéro d’acquisition GenBank: BC012885
• Symbole du gène: PLXDC2
• Identification du gène (NCBI): 84898
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PLXDC2 (Plexin-domain containing 2), also named tumor endothelial marker 7-related protein (TEM7R), is a single-pass type I membrane protein with some homology to nidogen and to plexins. PLXDC2 is located in tumor endothelium and plays a role in tumor angiogenesis. Three isoforms of PLXDC2 produced by alternative splicing have been described. Recent finding revealed that PLXDC2 is a mitogen for neural progenitors and functions as a novel regulator of the development of different brain regions, suggesting its role in coordinating proliferation and differentiation in the developing nervous system.

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