Anticorps Polyclonal de lapin anti-PLXNA4

PLXNA4 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17201-1-PBS

Synonymes

FAYV2820, KIAA1550, PLEXA4, plexin A4, Plexin-A4

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Galerie de données de validation

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  WB analysis using 17201-1-AP (same clone as 17201-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17201-1-AP (PLXNA4 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17201-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17201-1-PBS cible PLXNA4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PLXNA4 Protéine recombinante Ag10978
• Nom complet: plexin A4
• Masse moléculaire calculée: 522aa,58 kDa; 1894aa,212 kDa
• Poids moléculaire observé: 212 kDa
• Numéro d’acquisition GenBank: BC028744
• Symbole du gène: PLXNA4
• Identification du gène (NCBI): 91584
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PLXNA4 is a plexin family receptor that transduces semaphorin signals to regulate axon guidance, vascular development, and immune cell migration. It functions as a plasma membrane receptor with intracellular GTPase-regulatory activity, linking extracellular cues to cytoskeletal remodeling. Dysregulation of PLXNA4 has been associated with neurological disease (including Alzheimer's), cancer progression, and vascular/immune dysfunction, making it a multifunctional receptor of significant biomedical interest. (PMID: 27127761)

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