Anticorps Polyclonal de lapin anti-PNMA5

PNMA5 Polyclonal Antibody for WB, IHC, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 21770-1-PBS

Synonymes

KIAA1934, paraneoplastic antigen like 5

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Galerie de données de validation

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  WB analysis using 21770-1-AP (same clone as 21770-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21770-1-AP (PNMA5 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21770-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 21770-1-AP (same clone as 21770-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 21770-1-AP (PNMA5 antibody) at dilution of 1:800 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21770-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 21770-1-AP (same clone as 21770-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 21770-1-AP (PNMA5 antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21770-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse testis using 21770-1-AP (same clone as 21770-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse testis tissue using PNMA5 antibody (21770-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21770-1-PBS in a different storage buffer formulation.

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Informations sur le produit

21770-1-PBS cible PNMA5 dans les applications de WB, IHC, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PNMA5 Protéine recombinante Ag16414
• Nom complet: paraneoplastic antigen like 5
• Masse moléculaire calculée: 448 aa, 50 kDa
• Poids moléculaire observé: 50 kDa
• Numéro d’acquisition GenBank: BC101112
• Symbole du gène: PNMA5
• Identification du gène (NCBI): 114824
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PNMA5 is a member of the paraneoplastic Ma antigen (PNMA) family proteins which share relatively conserved protein sequences and are involved in the regulation of growth, apoptosis, or fate determination in different cell types (PMID: 29378289). PNMA5 appears to be involved in the association areas of the neocortex during primate evolution (PMID: 19366867). PNMA5 has been reported to play roles in the pathological development and metastasis of some cancers, including colorectal cancer, ovarian cancer, and lung cancer (PMID: 35559417; 35117731; 34136487).

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