Anticorps Polyclonal de lapin anti-PNRC2
PNRC2 Polyclonal Antibody for Indirect ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain, souris
Applications
Indirect ELISA
Conjugaison
Non conjugué
N° de cat : 51050-1-PBS
Synonymes
Galerie de données de validation
Informations sur le produit
51050-1-PBS cible PNRC2 dans les applications de Indirect ELISA et montre une réactivité avec des échantillons Humain, souris
| Réactivité | Humain, souris |
| Hôte / Isotype | Lapin / IgG |
| Clonalité | Polyclonal |
| Type | Anticorps |
| Immunogène | PNRC2 Protéine recombinante Ag0099 |
| Nom complet | proline-rich nuclear receptor coactivator 2 |
| Masse moléculaire calculée | 16 kDa |
| Poids moléculaire observé | 25 kDa |
| Numéro d’acquisition GenBank | BC001959 |
| Symbole du gène | PNRC2 |
| Identification du gène (NCBI) | 55629 |
| Conjugaison | Non conjugué |
| Forme | Liquide |
| Méthode de purification | Purification par affinité contre l'antigène |
| Tampon de stockage | PBS only |
| Conditions de stockage | Store at -80°C. 20ul contiennent 0,1% de BSA. |
Informations générales
PNRC2 belongs to the PNRC family and PNRC2 subfamily. It is Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. It is required for UPF1/RENT1 localization to the P-body. PNRC2 also acts as a nuclear receptor coactivator. It may play a role in controlling the energy balance between energy storage and energy expenditure. (PMID:19150429) PNRC2 functions as a coactivator of several nuclear receptors, including ERRa, and participates in the activation of aromatase in conjunction with ERRa. Growth factor signaling promotes PELP1 recruitment to the aromatase chromatin and its formation of a complex with ERRa and PNRC2.(PMID:18079323)
