Anticorps Monoclonal anti-PPA2

• Phare
• Validé par KD/KO

PPA2 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1C2E3

N° de cat : 68468-1-PBS

Synonymes

1C2E3, EC:3.6.1.1, HSPC124, PPase 2, Pyrophosphatase SID6 306

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Galerie de données de validation

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  WB analysis of HEK-293 using 68468-1-Ig (same clone as 68468-1-PBS)

  WB result of PPA2 antibody (68468-1-Ig; 1:6000; incubated at room temperature for 1.5 hours) with sh-Control and sh-PPA2 transfected HEK-293 cells. This data was developed using the same antibody clone with 68468-1-PBS in a different storage buffer formulation.

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  WB analysis using 68468-1-Ig (same clone as 68468-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68468-1-Ig (PPA2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Alpha Tubulin Monoclonal antibody (HRP-66031) as loading control. This data was developed using the same antibody clone with 68468-1-PBS in a different storage buffer formulation.

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  WB analysis of 4T1 using 68468-1-Ig (same clone as 68468-1-PBS)

  4T1 cells were subjected to SDS PAGE followed by western blot with 68468-1-Ig (PPA2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68468-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68468-1-PBS cible PPA2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: PPA2 Protéine recombinante Ag10125
• Nom complet: pyrophosphatase (inorganic) 2
• Masse moléculaire calculée: 305aa,35 kDa; 334aa,38 kDa
• Poids moléculaire observé: 34 kDa
• Numéro d’acquisition GenBank: BC057219
• Symbole du gène: PPA2
• Identification du gène (NCBI): 27068
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Pyrophosphatase 2 (PPA2) is a mitochondrial-located pyrophosphatase (PPase) that hydrolyzes inorganic pyrophosphate (PPi), generated by numerous nucleotide-dependent reactions, into two orthophosphate molecules (PMID: 34400813). PPA2 is a cardiomyopathy-associated protein, which has a greater physiological importance in mitochondrial function (PMID: 27523597).

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