Anticorps Recombinant de lapin anti-PPIL1

PPIL1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250902G7

N° de cat : 86312-1-PBS

Synonymes

CGI 124, CGI-124, CYPL1, EC:5.2.1.8, hCyPX

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Galerie de données de validation

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  WB analysis using 86312-1-RR (same clone as 86312-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86312-1-RR (PPIL1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86312-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86312-1-PBS cible PPIL1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: PPIL1 Protéine recombinante Ag7436
• Nom complet: peptidylprolyl isomerase (cyclophilin)-like 1
• Masse moléculaire calculée: 18 kDa
• Poids moléculaire observé: 18 kDa
• Numéro d’acquisition GenBank: BC003048
• Symbole du gène: PPIL1
• Identification du gène (NCBI): 51645
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Peptidyl-prolyl isomerase (PPIase) catalyzes the interconversion of a specific Pro-imide bond between the cis and trans conformations. PPIL1 (Peptidyl-prolyl cis-trans isomerase-like 1) is up-regulated in human colon cancer cells and an siRNA-mediated knockdown of PPIL1 resulted in a reduced number of viable cell (PMID: 20368803). Expression of PPIL1 was shown to be ubiquitous across all adult tissues (with highest expression in the adrenal gland, testis and heart). PPIL1 is also known to participate in the spliceosome; a complex and dynamic protein and RNA complex responsible for splicing introns from pre-mRNA (PMID: 33220177, 8978786).

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