Anticorps Polyclonal de lapin anti-PPP1R17

PPP1R17 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27976-1-PBS

Synonymes

---

Galerie de données de validation

• 

  WB analysis using 27976-1-AP (same clone as 27976-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27976-1-AP (C7orf16 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27976-1-PBS in a different storage buffer formulation.

• 

  IF Staining of U2OS using 27976-1-AP (same clone as 27976-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed U2OS cells using PPP1R17 antibody (27976-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 27976-1-PBS in a different storage buffer formulation.

• 

  IF Staining of U2OS using 27976-1-AP (same clone as 27976-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed U2OS cells using PPP1R17 antibody (27976-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 27976-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

27976-1-PBS cible PPP1R17 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PPP1R17 Protéine recombinante Ag15187
• Nom complet: chromosome 7 open reading frame 16
• Masse moléculaire calculée: 155 aa, 18 kDa
• Poids moléculaire observé: 20-30 kDa
• Numéro d’acquisition GenBank: BC028094
• Symbole du gène: PPP1R17
• Identification du gène (NCBI): 10842
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PPP1R17, an endogenous substrate for cGMP-dependent protein kinase, exists almost exclusively in cerebellar Purkinje cells, where it is possibly involved in the induction of long-term depression (PMID: 10051666). PPP1R17 inhibits phosphatase activities of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) complexes. Allelic variants increase susceptibility to hypercholesterolemia (PMID: 12955585).

{{ptg:RelatedPrimaryAntibodies}}