Anticorps Recombinant de lapin anti-PPP2CA

PPP2CA Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, porc, rat, souris

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241112A6

N° de cat : 84155-2-PBS

Synonymes

241112A6, EC:3.1.3.16, PP2A alpha, PP2A-alpha, PP2Ac

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Galerie de données de validation

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  WB analysis of HeLa using 84155-2-RR (same clone as 84155-2-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 84155-2-RR (PPP2CA antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84155-2-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP01058-2

  Cytometric bead array standard curve of MP01058-2, PPP2CA Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84155-2-PBS. Detection antibody: 84155-4-PBS. Standard: Ag4294. Range: 0.781-100 ng/mL.

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  Affinity and Kinetic Characterization of 84155-2-RR

  Biolayer interferometry (BLl) kinetic assays of 84155-2-RR against Human PPP2CA were performed. The affinity constant is 11.6 nM.

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Informations sur le produit

84155-2-PBS cible PPP2CA dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc, rat, souris

• Réactivité: Humain, porc, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: PPP2CA Protéine recombinante Ag4294
• Nom complet: protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
• Masse moléculaire calculée: 309 aa, 36 kDa
• Poids moléculaire observé: 36 kDa
• Numéro d’acquisition GenBank: BC031696
• Symbole du gène: PPP2CA
• Identification du gène (NCBI): 5515
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PPP2CA, also named as RP-C and PP2A-alpha, belongs to the PPP phosphatase family and PP-1 subfamily. PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. PP2A activity was modestly decreased in AML patients harboring C-KIT/WT.PP2A is a target for C-KIT/TKD and implicated the potential efficacy of therapies targeting PP2A in such AML in future.

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