Anticorps Monoclonal anti-Progesterone Receptor

Progesterone Receptor Monoclonal Antibody for IHC, ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

IHC, ELISA

Conjugaison

Non conjugué

CloneNo.

3D1D12

N° de cat : 66300-1-PBS

Synonymes

PGR, 3D1D12, NR3C3, PR, PRGR

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Galerie de données de validation

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  IHC staining of human breast cancer using 66300-1-Ig (same clone as 66300-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66300-1-Ig (Progesterone Receptor antibody) at dilution of 1:9900 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66300-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 66300-1-Ig (same clone as 66300-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66300-1-Ig (Progesterone Receptor antibody) at dilution of 1:9900 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66300-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 66300-1-Ig (same clone as 66300-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66300-1-Ig (Progesterone Receptor antibody) at dilution of 1:10000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66300-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66300-1-PBS cible Progesterone Receptor dans les applications de IHC, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Progesterone Receptor Protéine recombinante Ag22992
• Nom complet: progesterone receptor
• Masse moléculaire calculée: 933 aa, 99 kDa
• Numéro d’acquisition GenBank: NM_000926
• Symbole du gène: Progesterone Receptor
• Identification du gène (NCBI): 5241
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PGR (Progesterone Receptor), also named as NR3C3 and PR, belongs to the nuclear hormone receptor family and NR3 subfamily. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. The ER and PR status has been used as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence.

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