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Anticorps Polyclonal de lapin anti-PRDM6

PRDM6 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 33205-1-PBS

Synonymes

EC:2.1.1.361, PFM3, PR domain zinc finger protein 6, PR domain-containing protein 6, Putative histone-lysine N-methyltransferase PRDM6

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using PRDM6 Polyclonal antibody (33205-1-AP)

    WB analysis using 33205-1-AP (same clone as 33205-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 33205-1-AP (PRDM6 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33205-1-PBS in a different storage buffer formulation.

Informations sur le produit

33205-1-PBS cible PRDM6 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène PRDM6 Protéine recombinante Ag38054
Nom complet PR domain containing 6
Masse moléculaire calculée595aa, 64 kDa
Poids moléculaire observé75 kDa
Numéro d’acquisition GenBankNM_001136239
Symbole du gène PRDM6
Identification du gène (NCBI) 93166
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PRDM6 is a poorly characterized member of the PRDF1 and RIZ1 homology domain-containing (PRDM) family of transcription factors that possess histone lysine methyltransferase activities through their catalytic SET domain. Based on findings in other species, PRDM6 is currently classified as a pseudo-methyltransferase that may interact with the methyltransferase G9a and corepressors to indirectly affect the methylation status of histone H3 lysine and histone H4 lysine. PRDM6 inhibition may have therapeutic value in PRDM6-expressing medulloblastomas (PMID: 38992221). PRDM6 has one glycosylation modification site.

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