Anticorps Recombinant de lapin anti-PRKACB

PRKACB Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242947A6

N° de cat : 85716-2-PBS

Synonymes

EC:2.7.11.11, PKA C beta, PKA C-beta, PKACB

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Galerie de données de validation

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  WB analysis using 85716-2-RR (same clone as 85716-2-PBS)

  Fetal human brain tissue lysates were subjected to SDS PAGE followed by western blot with 85716-2-RR (PRKACB antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85716-2-PBS in a different storage buffer formulation.

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  WB analysis using 85716-2-RR (same clone as 85716-2-PBS)

  HeLa cell lysates were subjected to SDS PAGE followed by western blot with 85716-2-RR (PRKACB antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85716-2-PBS in a different storage buffer formulation.

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Informations sur le produit

85716-2-PBS cible PRKACB dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: protein kinase, cAMP-dependent, catalytic, beta
• Masse moléculaire calculée: 46 kDa
• Poids moléculaire observé: 36-46 kDa
• Numéro d’acquisition GenBank: NM_002731
• Symbole du gène: PRKACB
• Identification du gène (NCBI): 5567
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PRKACB, also named as PKA C-beta, belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family and cAMP subfamily. It mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux.

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