Anticorps Polyclonal de lapin anti-PRMT7

PRMT7 Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 21688-1-PBS

Synonymes

Protein arginine N-methyltransferase 7, PRMT 7, Histone-arginine N-methyltransferase PRMT7, EC:2.1.1.321, [Myelin basic protein]-arginine N-methyltransferase PRMT7

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Galerie de données de validation

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  WB analysis using 21688-1-AP (same clone as 21688-1-PBS)

  NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 21688-1-AP (PRMT7 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21688-1-PBS in a different storage buffer formulation.

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  WB analysis using 21688-1-AP (same clone as 21688-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21688-1-AP (PRMT7 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21688-1-PBS in a different storage buffer formulation.

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  IP experiment of HeLa using 21688-1-AP (same clone as 21688-1-PBS)

  IP result of anti-PRMT7 (IP:21688-1-AP, 4ug; Detection:21688-1-AP 1:1000) with HeLa cells lysate 1400 ug. This data was developed using the same antibody clone with 21688-1-PBS in a different storage buffer formulation.

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Informations sur le produit

21688-1-PBS cible PRMT7 dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PRMT7 Protéine recombinante Ag16269
• Nom complet: protein arginine methyltransferase 7
• Masse moléculaire calculée: 78 kDa
• Poids moléculaire observé: 73-78 kDa
• Numéro d’acquisition GenBank: BC000146
• Symbole du gène: PRMT7
• Identification du gène (NCBI): 54496
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Protein arginine methyltransferases (PRMTs) are responsible for arginine methylation of histone or nonhistone proteins to regulate diverse biological processes, including cell proliferation, differentiation and senescence. PRMT7 is expressed in both embryonic stem and germ cells and is implicated in maintenance of muscle stem cell function. overexpression of PRMT7 has been associated with cancer metastasis. PRMT7 automethylation at residue R531 was reported to enhance breast cancer metastasis.

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