Anticorps Monoclonal anti-PRODH

PRODH Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, Lapin, porc, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2C3G5

N° de cat : 68621-1-PBS

Synonymes

2C3G5, EC:1.5.5.2, HSPOX2, p53-induced gene 6 protein, PIG6

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Galerie de données de validation

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  WB analysis using 68621-1-Ig (same clone as 68621-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68621-1-Ig (PRODH antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68621-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68621-1-PBS cible PRODH dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, Lapin, porc, rat, souris

• Réactivité: Humain, Lapin, porc, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: PRODH Protéine recombinante Ag18429
• Nom complet: proline dehydrogenase (oxidase) 1
• Masse moléculaire calculée: 600 aa, 68 kDa
• Poids moléculaire observé: 56 kDa, 66 kDa
• Numéro d’acquisition GenBank: BC118597
• Symbole du gène: PRODH
• Identification du gène (NCBI): 5625
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PRODH(Proline dehydrogenase 1, mitochondrial) is also named as PIG6, HSPOX2, PRODH1, PRODH2, POX, SCZD4, TP53I6 and belongs to the proline oxidase family. It is an oxidoreductase involved in the transfer of redox potential across the mitochondrial membrane and catalyzes the rate-limiting oxidation of proline to pyrroline- 5-carboxylate (P5C). High PRODH activity is sufficient to induce mitochondria-mediated apoptosis in the presence of proline. Defects in PRODH are the cause of hyperprolinemia type 1 (HP-1) and defects in PRODH are associated with susceptibility to schizophrenia type 4 (SCZD4). This protein has 3 isoforms produced by alternative splicing with the molecular mass of 68 kDa, 59 kDa and 56 kDa.

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