Anticorps Monoclonal anti-PRPH2

PRPH2 Monoclonal Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain, Lapin, rat, souris

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2F11A1

N° de cat : 68780-1-PBS

Synonymes

2F11A1, AOFMD, AVMD, Peripherin 2, Peripherin2

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Galerie de données de validation

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  WB analysis using 68780-1-Ig (same clone as 68780-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68780-1-Ig (PRPH2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68780-1-PBS in a different storage buffer formulation.

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  WB analysis using 68780-1-Ig (same clone as 68780-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68780-1-Ig (PRPH2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68780-1-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP50146-1

  Cytometric bead array standard curve of MP50146-1, PRPH2 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68780-1-PBS. Detection antibody: 68780-2-PBS. Standard:Ag12555. Range: 1.563-100 ng/mL.

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  Affinity and Kinetic Characterization of 68780-1-Ig

  Biolayer interferometry (BLl) kinetic assay of 68780-1-Ig against Human PRPH2 was performed. The affinity constant is below 1 pM.

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Informations sur le produit

68780-1-PBS cible PRPH2 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain, Lapin, rat, souris

• Réactivité: Humain, Lapin, rat, souris
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: PRPH2 Protéine recombinante Ag12555
• Nom complet: peripherin 2 (retinal degeneration, slow)
• Masse moléculaire calculée: 346 aa, 39 kDa
• Poids moléculaire observé: 35-39 kDa
• Numéro d’acquisition GenBank: BC074720
• Symbole du gène: PRPH2
• Identification du gène (NCBI): 5961
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Peripherin-2 (PRPH2), also known as retinal degeneration slow protein (RDS), is a photoreceptor-specific tetraspanin protein implicated in outer segment disk morphogenesis. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Mutations in peripherin-2 are responsible for various retinal degenerative diseases including autosomal dominant retinitis pigmentosa (ADRP).

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