Anticorps Polyclonal de lapin anti-PRR11

PRR11 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27422-1-PBS

Synonymes

Proline rich protein 11, proline rich 11

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Galerie de données de validation

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  WB analysis using 27422-1-AP (same clone as 27422-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27422-1-AP (PRR11 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27422-1-PBS in a different storage buffer formulation.

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Informations sur le produit

27422-1-PBS cible PRR11 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PRR11 Protéine recombinante Ag26636
• Nom complet: proline rich 11
• Masse moléculaire calculée: 360 aa, 40 kDa
• Poids moléculaire observé: 38 kDa
• Numéro d’acquisition GenBank: BC008669
• Symbole du gène: PRR11
• Identification du gène (NCBI): 55771
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PRR11, or Proline-rich protein 11, is a protein-coding gene situated on chromosome 17q22-23, which plays a significant role in various cellular processes. The protein itself is composed of a nuclear localization signal (NLS), two proline-rich regions (PRs), and a zinc finger domain (ZFD) (PMID: 36551227). PRR11 has been implicated in the regulation of cell cycle, and it is involved in multiple aspects of cancer biology, including proliferation, migration, invasion, cell-cycle progression, apoptosis, autophagy, and chemotherapy resistance. It serves as a prognostic indicator in certain human cancers and is considered a potential target for therapeutic interventions (PMID: 36739300).

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