Anticorps Polyclonal de lapin anti-PSD95

PSD95 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30255-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 30255-1-AP (same clone as 30255-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30255-1-AP (PSD95 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30255-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 30255-1-AP (same clone as 30255-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 30255-1-AP (PSD95 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30255-1-PBS in a different storage buffer formulation.

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Informations sur le produit

30255-1-PBS cible PSD95 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PSD95 Protéine recombinante Ag33000
• Nom complet: discs, large homolog 4 (Drosophila)
• Masse moléculaire calculée: 81 kDa
• Poids moléculaire observé: 90-95 kDa
• Numéro d’acquisition GenBank: NM_001365
• Symbole du gène: PSD95
• Identification du gène (NCBI): 1742
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PSD-95 (postsynaptic density protein 95) also known as SAP-90 (synapse-associated protein 90) is a protein that in humans is encoded by the DLG4 (disks large homolog 4) gene. PSD-95 is a scaffolding protein of the MAGUK protein family, and engages in several vital protein-protein interactions in the brain with its PDZ domains. It has been suggested that PSD-95 is composed of two supramodules, one of which is the PDZ1-2 tandem domain. It plays an important role in synaptic plasticity and the stabilization of synaptic changes during long-term potentiation. Observed MW of PSD95 is 90-95 kDa due to phosphorylation (PMID: 20682303).

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