Anticorps Monoclonal anti-PSIP1

PSIP1 Monoclonal Antibody for Cytometric bead array, Sandwich ELISA, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

Cytometric bead array, Sandwich ELISA, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1C4G5

N° de cat : 68941-1-PBS

Synonymes

CLL associated antigen KW 7, CLL-associated antigen KW-7, DFS70, LEDGF, Lens epithelium-derived growth factor

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Galerie de données de validation

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  Sandwich ELISA sample test of MP50375-1

  The mean PSIP1 concentration was determined to be 89.0 ng/mL in HeLa cell extract based on a 1.1 mg/mL extract load, 25.7 ng/mL in HepG2 cell extract based on a 1.2 mg/mL extract load, 99.2 ng/mL in Jurkat cell extract based on a 1.2 mg/mL extract load and 26.7 ng/mL in MCF-7 cell extract based on a 1.2 mg/mL extract load.

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  Sandwich ELISA standard curve of MP50375-1

  Sandwich ELISA standard curve of MP50375-1, Human PSIP1 Monoclonal Matched Antibody Pair - PBS only. 67723-1-PBS was coated to a plate as the capture antibody and incubated with serial dilutions of standard Ag21886. 68941-1-PBS was HRP conjugated as the detection antibody. Range: 93.4-6000 pg/mL.

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  Cytometric bead array standard curve of MP50375-1

  Cytometric bead array standard curve of MP50375-1, PSIP1 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67723-1-PBS. Detection antibody: 68941-1-PBS. Standard:Ag21886. Range: 3.125-200 ng/mL.

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Informations sur le produit

68941-1-PBS cible PSIP1 dans les applications de Cytometric bead array, Sandwich ELISA, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: PSIP1 Protéine recombinante Ag21886
• Nom complet: PC4 and SFRS1 interacting protein 1
• Masse moléculaire calculée: 530 aa, 60 kDa
• Numéro d’acquisition GenBank: BC064135
• Symbole du gène: PSIP1
• Identification du gène (NCBI): 11168
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PSIP1, also known as PC4 and SRSF1 Interacting Protein 1 or Lens Epithelium-Derived Growth Factor (LEDGF), is a transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. It also plays a role in lens epithelial cell gene regulation and stress responses. It is a chromatin-associated protein with histone chaperone activity, involved in transcriptional elongation. PSIP1 may act as an adapter to coordinate pre-mRNA splicing. PSIP1 encodes two protein isoforms with molecular masses of 52 and 75 kDa. p52 and p75 were identified as interacting with transcription factor PC4 and shown to act as transcriptional coactivators.

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